Asojano

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Asojano is the Lord of Smallpox.

Carl, Donut, Sister Ines, Anton and Paz get a quest in which they get the option to repair his shrine. The description notes that repairing his shrine will not cause him to ascend.

AI Description

Observation Description:

Asojano - Orisha. Level 130 City Boss. This is a non-corporeal spirit.
Also known as the Lord of Smallpox, Asojano is one of the most respected and feared of the Orishas, a former god made flesh upon the rise of the Ascendency.
As the worshippers of these gods grew more and more extinct, their temples crumbled, and the power of these former deities waned. Eventually, they faded into nothing, slipping away beyond the veil, becoming nothing more than any other ghommid, only able to visit the physical world on occasion.
One day, not so long ago, Asojano found himself here in this small town, visiting the world he once helped rule. There was no malice to his actions. He came just so he could look upon what he once had and what he had lost.
Still, power lingers, even in the most forgotten of shells.
Asojano is disease incarnate. He kills, and he heals. He is life, and he is death. He also wears a reed hat that makes it difficult to see where he's going, so he bumps into stuff a lot. ^[1]

During the Thorn Room Boss Battle, if his shrine is repaired:

Asojano. The Lord of Smallpox. You know who this is. He’s the reason you’re in this pickle in the first place. If you repair his shrine, you will win the quest. The ghommids will all go back to normal. That’s it. Asojano will not ascend. He’s already proven he’s too much of a dangerous asshole to let back into the Halls of Ascendency.
But...
If you don’t repair his shrine, he will attack, and you will have to kill him. That’s the boss battle. Don’t forget that he’s a city boss! He will also break the protection of the chamber allowing the ghommids to surge into the temple. That will probably suck. Killing him will cure them. I hope.^[2]